Rare Diseases: Models & Mechanisms Network

Profile

Simmonds, Andrew

Basic Information

First Name
Last Name
Organization
Department
Website https://www.ualberta.ca/cellbiology/people/faculty/andrew-simmonds.html

Contact Information

Email andrew.simmonds@ualberta.ca
Phone 780-492-1840

About My Research

Fruit Fly Research Focus

Peroxisome function, muscle differentiation, mRNA regulation and localization, wing morphogenesis

Gene ID Symbol Name Tier
38994 Pex7 Peroxin 7 TIER1
43767 ci cubitus interruptus TIER3
44279 arr arrow TIER3
47594 aPKC atypical protein kinase C TIER3
33978 Hmgcl 3-Hydroxymethyl-3-methylglutaryl-CoA lyase TIER1
43420 wat waterproof TIER3
42049 Irc Immune-regulated catalase TIER3
42023 CG14893 uncharacterized protein TIER3
31522 CG4020 uncharacterized protein TIER3
3772165 Pex6 Peroxin 6 TIER1
41919 spn-E spindle E TIER3
43811 myo myoglianin TIER3
38412 Strip Striatin interacting protein TIER3
38004 gsb-n gooseberry-neuro TIER3
33474 daw dawdle TIER3
2768725 CG33474 uncharacterized protein TIER3
34524 aub aubergine TIER3
45460 Pex1 Peroxin 1 TIER1
38941 Pex2 Peroxin 2 TIER1
32771 mnb minibrain TIER3
35576 Mob4 MOB kinase activator 4 TIER3
34066 r2d2 r2d2 TIER3
43332 CROT Carnitine O-octanoyltransferase TIER1
41935 Fbxl7 F-box and leucine-rich repeat protein 7 TIER3
32582 Mfe2 peroxisomal Multifunctional enzyme type 2 TIER1
34630 Pex19 Peroxin 19 TIER1
36999 Smurf SMAD specific E3 ubiquitin protein ligase TIER3
42074 CG5265 uncharacterized protein TIER3
42022 CG17560 uncharacterized protein TIER3
36860 CG5065 uncharacterized protein TIER1
3771756 CG10097 uncharacterized protein TIER3
42751 Pex11c Peroxin 11c TIER1
38205 CG7970 uncharacterized protein TIER1
36669 Agps Alkylglycerone phosphate synthase TIER1
36990 POSH Plenty of SH3s TIER3
37528 Fmr1 Fragile X messenger ribonucleoprotein 1 TIER3
31141 Pex5 Peroxin 5 TIER1
44183 ScpX Sterol carrier protein X-related thiolase TIER2
37285 Hacl 2-hydroxyacyl-CoA lyase TIER1
37823 Phm Peptidylglycine-alpha-hydroxylating monooxygenase TIER3
37146 CG30122 uncharacterized protein TIER1
42734 Rassf Ras association family member TIER3
38760 sgl sugarless TIER3
38005 gsb gooseberry TIER3
32078 dsh dishevelled TIER3
44843 nkd naked cuticle TIER3
35742 Cul1 Cullin 1 TIER3
31698 p115 p115 TIER3
43318 CG5611 uncharacterized protein TIER1
45826 bel belle TIER3
43804 mav maverick TIER3
41704 rdx roadkill TIER3
41140 Ras85D Ras oncogene at 85D TIER3
31151 arm armadillo TIER3
40090 fz2 frizzled 2 TIER3
36462 Pex13 Peroxin 13 TIER1
42737 hh hedgehog TIER3
40177 Grasp65 Grasp65 TIER3
2768940 Pp2A-29B Protein phosphatase 2A at 29B TIER3
34891 dao down and out TIER1
34188 Sgp Sgroppino TIER3
39013 dally division abnormally delayed TIER3
3355127 Slmap Sarcolemma associated protein TIER3
33971 Fgop2 Fibroblast growth factor receptor 1 oncogene partner 2 TIER3
5740152 CG34342 uncharacterized protein TIER3
38657 vn vein TIER3
39943 frc fringe connection TIER3
32348 CG11095 uncharacterized protein TIER1
43718 pygo pygopus TIER3
39596 dlp dally-like TIER3
42833 CG12268 uncharacterized protein TIER3
34179 dachs dachs TIER3
3772183 CG10096 uncharacterized protein TIER3
35231 CG10194 uncharacterized protein TIER1
33131 wap wings apart TIER3
35717 tor torso TIER3
38355 CPT2 Carnitine palmitoyltransferase 2 TIER3
41026 CG8032 uncharacterized protein TIER1
44098 rasp rasp TIER3
32992 Abcd3 ATP binding cassette subfamily D member 3 TIER3
32723 B-H2 BarH2 TIER3
37973 Dll Distal-less TIER3
36758 Pex11ab Peroxin 11a/b TIER1
34198 CatB Catalase B TIER1
33955 Daao2 D-amino acid oxidase 2 TIER1
36029 CG1441 uncharacterized protein TIER3
2768852 par-1 par-1 TIER3
35430 tsh teashirt TIER3
317824 Zyx Zyxin TIER3
35213 CG17544 uncharacterized protein TIER1
43769 pan pangolin TIER3
3772365 RNaseMRP:RNA Ribonuclease MRP RNA TIER1
42693 Dcr-1 Dicer-1 TIER3
38736 sfl sulfateless TIER3
32351 jub Ajuba LIM protein TIER3
40196 CG14186 uncharacterized protein TIER1
31813 Lim1 LIM homeobox 1 TIER3
37445 Acox57D-p acyl-Coenzyme A oxidase at 57D proximal TIER3
36421 vg vestigial TIER1
34885 vig vasa intronic gene TIER3
32724 B-H1 BarH1 TIER3
39259 wls wntless TIER3
44275 SoxN SoxNeuro TIER3
42253 Mekk1 Mekk1 TIER3
35900 babo baboon TIER3
45707 FarO Fatty acyl-CoA reductase in oenocytes TIER3
37028 ACOX1 acyl-CoA oxidase 1 TIER1
40830 bcd bicoid TIER3
43095 Tnks tankyrase TIER3
38182 Pex10 Peroxin 10 TIER1
43772 Abcd1 ATP binding cassette subfamily D member 1 TIER1
36993 Dcr-2 Dicer-2 TIER3
31170 Sik2 Salt-inducible kinase 2 TIER3
42375 CG4770 uncharacterized protein TIER3
40787 CRAT Carnitine O-Acetyl-Transferase TIER1
34780 p38b p38b MAP kinase TIER3
39251 Sod1 Superoxide dismutase 1 TIER1
35509 ap apterous TIER3
45959 mts microtubule star TIER3
42757 pnt pointed TIER3
31248 sgg shaggy TIER3
36125 stan starry night TIER3
39683 AGO2 Argonaute 2 TIER1
37446 Acox57D-d acyl-Coenzyme A oxidase at 57D distal TIER3
41957 Akt Akt kinase TIER3
35337 Amacr Alpha-methylacyl-CoA racemase TIER1
32855 fu fused TIER3
40690 CG12171 uncharacterized protein TIER1
44274 disp dispatched TIER3
34096 Cka Connector of kinase to AP-1 TIER3
38244 Rap1 Rap1 GTPase TIER3
33445 Drp1 Dynamin related protein 1 TIER3
40048 Cat Catalase TIER1
45307 fz frizzled TIER3
34573 Dlg5 Discs large 5 TIER3
34009 wg wingless TIER1
36109 whd withered TIER3
42504 slmb supernumerary limbs TIER3
34703 CG5122 uncharacterized protein TIER1
53586 Gnpat Glyceronephosphate O-acyltransferase TIER3
318824 dpy dumpy TIER3
38070 Hipk Homeodomain interacting protein kinase TIER3
44856 ru roughoid TIER3
33245 ds dachsous TIER3
32221 CkIalpha Casein kinase Ialpha TIER3
40248 Ide Insulin degrading metalloproteinase TIER1
32169 Usp7 Ubiquitin-specific protease 7 TIER3
42871 Apc2 Adenomatous polyposis coli 2 TIER3
3772015 nw narrow TIER3
36128 Daao1 D-amino acid oxidase 1 TIER1
37152 Sik3 Salt-inducible kinase 3 TIER3
36857 CG8306 uncharacterized protein TIER3
43791 lgs legless TIER3
41370 Sptz Spastizin TIER1
40294 Pex14 Peroxin 14 TIER1
42021 CG17562 uncharacterized protein TIER3
35555 jing jing TIER3
43826 Actbeta Activin-beta TIER3
39652 Pex3 Peroxin 3 TIER1
3771728 anox anorexia TIER1
36032 Mef2 Myocyte enhancer factor 2 TIER1
36544 AGO1 Argonaute-1 TIER1
49892 Fis1 Fission, mitochondrial 1 TIER3
34982 dac dachshund TIER3
41275 Phyhd1 Phytanoyl-CoA dioxygenase domain containing 1 TIER1
44642 Apc APC-like TIER3
31641 CG4586 uncharacterized protein TIER3
42733 Cow Carrier of Wingless TIER3
31016 SkpA SKP1-related A TIER3
32257 lic licorne TIER3
37455 Egfr Epidermal growth factor receptor TIER3
36240 en engrailed TIER3
38045 Tudor-SN Tudor staphylococcal nuclease TIER3
32415 CG9519 uncharacterized protein TIER1
33196 smo smoothened TIER3
3354888 rl rolled TIER3
31738 Smox Smad on X TIER3
38151 Herc4 HECT and RLD domain containing E3 ubiquitin ligase 4 TIER3
36858 CG8303 uncharacterized protein TIER3
37986 CG30427 uncharacterized protein TIER3
37014 Dlish Dachs ligand with SH3s TIER3
40293 Pex16 Peroxin 16 TIER1
38168 rho rhomboid TIER3
3771779 Hao Hydroxyacid oxidase TIER1
32536 sd scalloped TIER1
38489 Ack Activated Cdc42 kinase TIER3
32935 pcm pacman TIER1
39521 Tgi Tondu-domain-containing Growth Inhibitor TIER1
43565 Axn Axin TIER3
43808 gw gawky TIER1
41786 smp-30 Senescence marker protein-30 TIER3
36033 Pal1 Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 1 TIER3
45318 kn knot TIER3
33256 Pex12 Peroxin 12 TIER1
33898 Acox3 Acyl-CoA oxidase 3 TIER3
32579 disco disconnected TIER3
Term Name Aspect Overlap Size
GO:0007367 segment polarity determination BP 3 40
GO:0001561 fatty acid alpha-oxidation BP 2 2
GO:0016560 protein import into peroxisome matrix, docking BP 3 3
GO:0004096 catalase activity MF 2 2
GO:0042760 very long-chain fatty acid catabolic process BP 4 5
GO:0016442 RISC complex CC 3 99
GO:0008445 D-aspartate oxidase activity MF 0 0
GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity MF 1 17
GO:0016559 peroxisome fission BP 2 7
GO:0035331 negative regulation of hippo signaling BP 0 50
GO:0016406 carnitine O-acyltransferase activity MF 3 6
GO:0044719 regulation of imaginal disc-derived wing size BP 0 14
GO:0003997 acyl-CoA oxidase activity MF 2 6
GO:0007449 proximal/distal pattern formation, imaginal disc BP 1 19
GO:0000268 peroxisome targeting sequence binding MF 3 3
GO:0008611 ether lipid biosynthetic process BP 2 3
GO:0030423 global gene silencing by mRNA cleavage BP 0 0