Rare Diseases: Models & Mechanisms Network

Profile

Verheyen, Esther

Basic Information

First Name
Last Name
Organization
Department
Website https://verheyenlab.weebly.com

Contact Information

Email everheye@sfu.ca
Phone 778-782-4665

About My Research

Human Organ Systems

Appendage
Eye
Musculature
Nervous system
Digestive system

Fruit Fly Research Focus

Drosophila

Gene ID Symbol Name Tier
31151 arm armadillo TIER1
37152 Sik3 Salt-inducible kinase 3 TIER1
31170 Sik2 Salt-inducible kinase 2 TIER1
38070 Hipk Homeodomain interacting protein kinase TIER1
44885 mys myospheroid TIER2
42504 slmb supernumerary limbs TIER2
32078 dsh dishevelled TIER1
31872 Dsor1 Downstream of raf1 TIER1
39157 Cdk8 Cyclin-dependent kinase 8 TIER1
33432 dpp decapentaplegic TIER1
42737 hh hedgehog TIER2
33529 Mad Mothers against dpp TIER2
34009 wg wingless TIER1
38890 nmo nemo TIER1
43991 Pten Phosphatase and tensin homolog TIER1
31293 N Notch TIER1
35486 sxc super sex combs TIER1
Term Name Aspect Overlap Size

Publications

PubMed ID Title
17507407
20398650
28236976 Homeodomain-Interacting Protein Kinases: Diverse and Complex Roles in Development and Disease.
34240146 Metabolic reprogramming in cancer: mechanistic insights from Drosophila.
29208636 Homeodomain-interacting protein kinase promotes tumorigenesis and metastatic cell behavior.
19065265
24821423
19623618
24880113
26542023
22840522
32820595 LRP6 lets Merlin go in times of nutrient scarcity.
32187190 Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure ...
24631217
25533344
8913755
27420097 Mammary Development and Breast Cancer: A Wnt Perspective.
26224310
22394486
21628596
19013449
25852200
35348663 The power of Drosophila in modeling human disease mechanisms.
18757943
31932432 The nutrient sensor OGT regulates Hipk stability and tumorigenic-like activities in Drosophila...
12385750
28652317 The protein phosphatase 4 complex promotes the Notch pathway and <i>wingless</i> tran...
34492006 A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of ...
15169756
37854071 The AMPK-like protein kinases Sik2 and Sik3 interact with Hipk and induce synergistic tumorigenes...
34849772 Expression of human HIPKs in Drosophila demonstrates their shared and unique functions in a devel...
20569681
19088090
21552260
36916233 Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominan...
25848695
31891940 Hipk is required for JAK/STAT activity during development and tumorigenesis.
31259690 A positive feedback loop between Myc and aerobic glycolysis sustains tumor growth in a Drosoph...
30540525 Actomyosin contractility modulates Wnt signaling through adherens junction stability.
18061555
11231065
22634475
26815659 A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Ju...

Last modified on January 16, 2024.