Rare Diseases: Models & Mechanisms Network

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Weaver, Ian

Basic Information

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Last Name
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Website https://www.dal.ca/faculty/science/psychology_neuroscience/faculty-staff/our-faculty/weaver-ian.html

Contact Information

Email ian.weaver@dal.ca
Phone 9024941133

About My Research

Human Cell Models Research Focus

Epigenetics, DNA methylation, gene expression, histone modifications, chromatin, immunometabolism, cell growth, apoptosis, anxiety (stress), learning and memory, social interaction, developmental disorders (autism), metabolic disease (triple-negative breast cancer, lung cancer), neurodegeneration (Niemann Pick disease, Alzhiemer's disease)

Gene ID Symbol Name Tier
5252 PHF1 PHD finger protein 1 TIER3
55611 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 TIER3
359787 DPPA3 developmental pluripotency associated 3 TIER3
5981 RFC1 replication factor C subunit 1 TIER3
2475 MTOR mechanistic target of rapamycin kinase TIER1
26036 ZNF451 zinc finger protein 451 TIER3
54908 SPDL1 spindle apparatus coiled-coil protein 1 TIER3
991 CDC20 cell division cycle 20 TIER3
6198 RPS6KB1 ribosomal protein S6 kinase B1 TIER3
10459 MAD2L2 mitotic arrest deficient 2 like 2 TIER3
78990 OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 TIER3
285051 STPG4 sperm-tail PG-rich repeat containing 4 TIER3
10919 EHMT2 euchromatic histone lysine methyltransferase 2 TIER3
7014 TERF2 telomeric repeat binding factor 2 TIER3
8550 MAPKAPK5 MAPK activated protein kinase 5 TIER3
6233 RPS27A ribosomal protein S27a TIER3
9869 SETDB1 SET domain bifurcated histone lysine methyltransferase 1 TIER3
346171 ZFP57 ZFP57 zinc finger protein TIER3
60488 MRPS35 mitochondrial ribosomal protein S35 TIER3
56852 RAD18 RAD18 E3 ubiquitin protein ligase TIER3
1789 DNMT3B DNA methyltransferase 3 beta TIER3
5885 RAD21 RAD21 cohesin complex component TIER3
5347 PLK1 polo like kinase 1 TIER3
7291 TWIST1 twist family bHLH transcription factor 1 TIER3
50943 FOXP3 forkhead box P3 TIER3
11335 CBX3 chromobox 3 TIER3
1026 CDKN1A cyclin dependent kinase inhibitor 1A TIER3
57599 WDR48 WD repeat domain 48 TIER3
10155 TRIM28 tripartite motif containing 28 TIER3
64949 MRPS26 mitochondrial ribosomal protein S26 TIER3
9183 ZW10 zw10 kinetochore protein TIER3
1642 DDB1 damage specific DNA binding protein 1 TIER3
140690 CTCFL CCCTC-binding factor like TIER3
3550 IK IK cytokine TIER3
339 APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 TIER3
11022 TDRKH tudor and KH domain containing TIER3
84944 MAEL maelstrom spermatogenic transposon silencer TIER3
127933 UHMK1 U2AF homology motif kinase 1 TIER3
64863 METTL4 methyltransferase 4, N6-adenosine TIER3
6119 RPA3 replication protein A3 TIER3
1788 DNMT3A DNA methyltransferase 3 alpha TIER3
3159 HMGA1 high mobility group AT-hook 1 TIER3
5425 POLD2 DNA polymerase delta 2, accessory subunit TIER3
2353 FOS Fos proto-oncogene, AP-1 transcription factor subunit TIER3
5424 POLD1 DNA polymerase delta 1, catalytic subunit TIER3
25913 POT1 protection of telomeres 1 TIER3
55196 RESF1 retroelement silencing factor 1 TIER3
55170 PRMT6 protein arginine methyltransferase 6 TIER3
10657 KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 TIER3
2778 GNAS GNAS complex locus TIER3
6830 SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor TIER3
11091 WDR5 WD repeat domain 5 TIER3
9555 MACROH2A1 macroH2A.1 histone TIER3
377630 USP17L2 ubiquitin specific peptidase 17 like family member 2 TIER3
7316 UBC ubiquitin C TIER3
56984 PSMG2 proteasome assembly chaperone 2 TIER3
5433 POLR2D RNA polymerase II subunit D TIER3
6188 RPS3 ribosomal protein S3 TIER3
10744 PTTG2 pituitary tumor-transforming 2 TIER3
200424 TET3 tet methylcytosine dioxygenase 3 TIER3
440275 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 TIER3
6622 SNCA synuclein alpha TIER3
54984 PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 TIER3
9463 PICK1 protein interacting with PRKCA 1 TIER3
1618 DAZL deleted in azoospermia like TIER3
672 BRCA1 BRCA1 DNA repair associated TIER3
57379 AICDA activation induced cytidine deaminase TIER3
10062 NR1H3 nuclear receptor subfamily 1 group H member 3 TIER3
7311 UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 TIER3
7398 USP1 ubiquitin specific peptidase 1 TIER3
4864 NPC1 NPC intracellular cholesterol transporter 1 TIER2
51409 HEMK1 HemK methyltransferase 1, mitochondrial release factors N(5)-glutamine TIER3
11277 TREX1 three prime repair exonuclease 1 TIER3
54880 BCOR BCL6 corepressor TIER3
55904 KMT2E lysine methyltransferase 2E (inactive) TIER3
26255 PTTG3P pituitary tumor-transforming 3, pseudogene TIER3
7320 UBE2B ubiquitin conjugating enzyme E2 B TIER3
9125 CNOT9 CCR4-NOT transcription complex subunit 9 TIER3
253943 YTHDF3 YTH N6-methyladenosine RNA binding protein F3 TIER3
5436 POLR2G RNA polymerase II subunit G TIER3
54915 YTHDF1 YTH N6-methyladenosine RNA binding protein F1 TIER3
1063 CENPF centromere protein F TIER3
25942 SIN3A SIN3 transcription regulator family member A TIER3
56165 TDRD1 tudor domain containing 1 TIER3
54386 TERF2IP TERF2 interacting protein TIER3
5983 RFC3 replication factor C subunit 3 TIER3
4690 NCK1 NCK adaptor protein 1 TIER3
51366 UBR5 ubiquitin protein ligase E3 component n-recognin 5 TIER3
6199 RPS6KB2 ribosomal protein S6 kinase B2 TIER3
9219 MTA2 metastasis associated 1 family member 2 TIER3
1617 DAZ1 deleted in azoospermia 1 TIER3
406958 MIR182 microRNA 182 TIER3
6659 SOX4 SRY-box transcription factor 4 TIER3
4255 MGMT O-6-methylguanine-DNA methyltransferase TIER3
55011 PIH1D1 PIH1 domain containing 1 TIER3
55818 KDM3A lysine demethylase 3A TIER3
64965 MRPS9 mitochondrial ribosomal protein S9 TIER3
4750 NEK1 NIMA related kinase 1 TIER3
136991 ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 TIER3
8091 HMGA2 high mobility group AT-hook 2 TIER3
8872 CDC123 cell division cycle 123 TIER3
54456 MOV10L1 Mov10 like RNA helicase 1 TIER3
7015 TERT telomerase reverse transcriptase TIER3
51384 WNT16 Wnt family member 16 TIER3
2146 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit TIER3
1200 TPP1 tripeptidyl peptidase 1 TIER3
51514 DTL denticleless E3 ubiquitin protein ligase homolog TIER3
56339 METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit TIER3
55124 PIWIL2 piwi like RNA-mediated gene silencing 2 TIER3
472 ATM ATM serine/threonine kinase TIER1
5079 PAX5 paired box 5 TIER3
201164 PLD6 phospholipase D family member 6 TIER3
26271 FBXO5 F-box protein 5 TIER3
9184 BUB3 BUB3 mitotic checkpoint protein TIER3
1487 CTBP1 C-terminal binding protein 1 TIER3
6867 TACC1 transforming acidic coiled-coil containing protein 1 TIER3
163589 TDRD5 tudor domain containing 5 TIER3
11284 PNKP polynucleotide kinase 3'-phosphatase TIER3
142 PARP1 poly(ADP-ribose) polymerase 1 TIER3
6598 SMARCB1 SWI/SNF related BAF chromatin remodeling complex subunit B1 TIER3
79813 EHMT1 euchromatic histone lysine methyltransferase 1 TIER3
324 APC APC regulator of WNT signaling pathway TIER3
80351 TNKS2 tankyrase 2 TIER3
5982 RFC2 replication factor C subunit 2 TIER3
22925 PLA2R1 phospholipase A2 receptor 1 TIER3
122402 TDRD9 tudor domain containing 9 TIER3
23411 SIRT1 sirtuin 1 TIER3
8450 CUL4B cullin 4B TIER3
7157 TP53 tumor protein p53 TIER3
9474 ATG5 autophagy related 5 TIER3
23645 PPP1R15A protein phosphatase 1 regulatory subunit 15A TIER3
3720 JARID2 jumonji and AT-rich interaction domain containing 2 TIER3
9370 ADIPOQ adiponectin, C1Q and collagen domain containing TIER3
23081 KDM4C lysine demethylase 4C TIER3
54496 PRMT7 protein arginine methyltransferase 7 TIER3
65057 ACD ACD shelterin complex subunit and telomerase recruitment factor TIER3
143689 PIWIL4 piwi like RNA-mediated gene silencing 4 TIER3
7756 ZNF207 zinc finger protein 207 TIER3
23272 TASOR transcription activation suppressor TIER3
3070 HELLS helicase, lymphoid specific TIER3
23367 LARP1 La ribonucleoprotein 1, translational regulator TIER3
56848 SPHK2 sphingosine kinase 2 TIER3
54505 DHX29 DExH-box helicase 29 TIER3
80764 THAP7 THAP domain containing 7 TIER3
55364 IMPACT impact RWD domain protein TIER3
6497 SKI SKI proto-oncogene TIER3
5985 RFC5 replication factor C subunit 5 TIER3
8493 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D TIER3
4302 MLLT6 MLLT6, PHD finger containing TIER3
55729 ATF7IP activating transcription factor 7 interacting protein TIER3
4085 MAD2L1 mitotic arrest deficient 2 like 1 TIER3
6688 SPI1 Spi-1 proto-oncogene TIER3
54514 DDX4 DEAD-box helicase 4 TIER3
57343 ZNF304 zinc finger protein 304 TIER3
6879 TAF7 TATA-box binding protein associated factor 7 TIER3
8658 TNKS tankyrase TIER3
8927 BSN bassoon presynaptic cytomatrix protein TIER3
23028 KDM1A lysine demethylase 1A TIER3
57135 DAZ4 deleted in azoospermia 4 TIER3
1029 CDKN2A cyclin dependent kinase inhibitor 2A TIER3
57673 BEND3 BEN domain containing 3 TIER3
699 BUB1 BUB1 mitotic checkpoint serine/threonine kinase TIER3
4552 MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase TIER3
10714 POLD3 DNA polymerase delta 3, accessory subunit TIER3
55929 DMAP1 DNA methyltransferase 1 associated protein 1 TIER3
27445 PCLO piccolo presynaptic cytomatrix protein TIER3
56155 TEX14 testis expressed 14, intercellular bridge forming factor TIER3
22880 MORC2 MORC family CW-type zinc finger 2 TIER3
84861 KLHL22 kelch like family member 22 TIER3
9212 AURKB aurora kinase B TIER3
8379 MAD1L1 mitotic arrest deficient 1 like 1 TIER3
64963 MRPS11 mitochondrial ribosomal protein S11 TIER3
5984 RFC4 replication factor C subunit 4 TIER3
7520 XRCC5 X-ray repair cross complementing 5 TIER3
57804 POLD4 DNA polymerase delta 4, accessory subunit TIER3
6418 SET SET nuclear proto-oncogene TIER3
1654 DDX3X DEAD-box helicase 3 X-linked TIER3
5611 DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 TIER3
9733 SART3 spliceosome associated factor 3, U4/U6 recycling protein TIER3
27136 MORC1 MORC family CW-type zinc finger 1 TIER3
22823 MTF2 metal response element binding transcription factor 2 TIER3
5111 PCNA proliferating cell nuclear antigen TIER3
6352 CCL5 C-C motif chemokine ligand 5 TIER3
9320 TRIP12 thyroid hormone receptor interactor 12 TIER3
26277 TINF2 TERF1 interacting nuclear factor 2 TIER3
7272 TTK TTK protein kinase TIER3
5927 KDM5A lysine demethylase 5A TIER3
57054 DAZ3 deleted in azoospermia 3 TIER3
54737 MPHOSPH8 M-phase phosphoprotein 8 TIER3
54815 GATAD2A GATA zinc finger domain containing 2A TIER3
546 ATRX ATRX chromatin remodeler TIER1
6118 RPA2 replication protein A2 TIER3
22927 HABP4 hyaluronan binding protein 4 TIER3
340602 EZHIP EZH inhibitory protein TIER3
221656 KDM1B lysine demethylase 1B TIER3
83852 SETDB2 SET domain bifurcated histone lysine methyltransferase 2 TIER3
1432 MAPK14 mitogen-activated protein kinase 14 TIER3
51535 PPHLN1 periphilin 1 TIER3
6256 RXRA retinoid X receptor alpha TIER1
434 ASIP agouti signaling protein TIER3
755 CFAP410 cilia and flagella associated protein 410 TIER3
26155 NOC2L NOC2 like nucleolar associated transcriptional repressor TIER3
79035 NABP2 nucleic acid binding protein 2 TIER3
7124 TNF tumor necrosis factor TIER3
29947 DNMT3L DNA methyltransferase 3 like TIER3
9232 PTTG1 PTTG1 regulator of sister chromatid separation, securin TIER3
8260 NAA10 N-alpha-acetyltransferase 10, NatA catalytic subunit TIER3
8451 CUL4A cullin 4A TIER3
7349 UCN urocortin TIER3
10664 CTCF CCCTC-binding factor TIER3
11176 BAZ2A bromodomain adjacent to zinc finger domain 2A TIER3
1786 DNMT1 DNA methyltransferase 1 TIER3
91646 TDRD12 tudor domain containing 12 TIER3
545 ATR ATR checkpoint kinase TIER3
9319 TRIP13 thyroid hormone receptor interactor 13 TIER3
57055 DAZ2 deleted in azoospermia 2 TIER3
675 BRCA2 BRCA2 DNA repair associated TIER3
406 BMAL1 basic helix-loop-helix ARNT like 1 TIER3
6117 RPA1 replication protein A1 TIER3
701 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B TIER3
8893 EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon TIER3
29104 HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine TIER3
7175 TPR translocated promoter region, nuclear basket protein TIER3
8468 FKBP6 FKBP prolyl isomerase family member 6 (inactive) TIER3
51441 YTHDF2 YTH N6-methyladenosine RNA binding protein F2 TIER3
9978 RBX1 ring-box 1 TIER3
7314 UBB ubiquitin B TIER3
80312 TET1 tet methylcytosine dioxygenase 1 TIER3
195814 SDR16C5 short chain dehydrogenase/reductase family 16C member 5 TIER3
57472 CNOT6 CCR4-NOT transcription complex subunit 6 TIER3
66037 BOLL boule homolog, RNA binding protein TIER3
55693 KDM4D lysine demethylase 4D TIER3
Term Name Aspect Overlap Size
GO:0042769 obsolete DNA damage response, detection of DNA damage BP 0 0
GO:0070994 detection of oxidative stress BP 0 2
GO:0032776 obsolete DNA methylation on cytosine BP 0 0
GO:0035985 senescence-associated heterochromatin focus CC 0 4
GO:0031637 regulation of neuronal synaptic plasticity in response to neurotrophin BP 0 0
GO:0090308 obsolete regulation of DNA methylation-dependent heterochromatin formation BP 0 0
GO:1903586 obsolete positive regulation of histone deubiquitination BP 0 0
GO:0031057 obsolete negative regulation of histone modification BP 0 0
GO:0040030 obsolete regulation of molecular function, epigenetic BP 0 0
GO:0099526 presynapse to nucleus signaling pathway BP 0 0
GO:0033048 negative regulation of mitotic sister chromatid segregation BP 1 33
GO:0006306 obsolete DNA methylation BP 0 0
GO:0045948 positive regulation of translational initiation BP 1 30
GO:0090400 stress-induced premature senescence BP 0 8
GO:2000325 obsolete regulation of nuclear receptor coactivator activity BP 0 0
GO:0070198 protein localization to chromosome, telomeric region BP 1 17

Mouse Research Focus

Epigenetics, DNA methylation, gene expression, histone modifications, chromatin, immunometabolism, cell growth, apoptosis, anxiety (stress), learning and memory, social interaction, developmental disorders (autism), metabolic disease (triple-negative breast cancer, lung cancer), neurodegeneration (Niemann Pick disease, Alzhiemer's disease)

Gene ID Symbol Name Tier
230709 Zmpste24 zinc metallopeptidase, STE24 TIER3
22209 Ube2a ubiquitin-conjugating enzyme E2A TIER3
226153 Twnk twinkle mtDNA helicase TIER3
81897 Tlr9 toll-like receptor 9 TIER3
100040462 Mndal myeloid nuclear differentiation antigen like TIER3
216850 Kdm6b KDM1 lysine (K)-specific demethylase 6B TIER3
12151 Bmi1 Bmi1 polycomb ring finger oncogene TIER3
68845 Pih1d1 PIH1 domain containing 1 TIER3
20586 Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 TIER3
17193 Mbd4 methyl-CpG binding domain protein 4 TIER3
67014 Riox2 ribosomal oxygenase 2 TIER3
68550 Tefm transcription elongation factor, mitochondrial TIER3
100033459 Ifi208 interferon activated gene 208 TIER3
11865 Bmal1 basic helix-loop-helix ARNT like 1 TIER3
22608 Ybx1 Y box protein 1 TIER3
75605 Kdm5b lysine demethylase 5B TIER3
57746 Piwil2 piwi-like RNA-mediated gene silencing 2 TIER3
214498 Cdc73 cell division cycle 73, Paf1/RNA polymerase II complex component TIER3
23797 Akt3 thymoma viral proto-oncogene 3 TIER3
99982 Kdm1a lysine (K)-specific demethylase 1A TIER3
15258 Hipk2 homeodomain interacting protein kinase 2 TIER3
117599 Helb helicase (DNA) B TIER3
21402 Skp1 S-phase kinase-associated protein 1 TIER3
54683 Prdx5 peroxiredoxin 5 TIER3
75467 Stpg4 sperm tail PG rich repeat containing 4 TIER3
75736 Bcl2l12 BCL2 like 12 TIER3
242285 Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 TIER3
57295 Icmt isoprenylcysteine carboxyl methyltransferase TIER3
13435 Dnmt3a DNA methyltransferase 3A TIER3
67917 Zcchc3 zinc finger, CCHC domain containing 3 TIER3
238328 Vash1 vasohibin 1 TIER3
14815 Nr3c1 nuclear receptor subfamily 3, group C, member 1 TIER2
230674 Kdm4a lysine (K)-specific demethylase 4A TIER3
24074 Taf7 TATA-box binding protein associated factor 7 TIER3
71041 Pcgf6 polycomb group ring finger 6 TIER3
22226 Ucn urocortin TIER3
13982 Esr1 estrogen receptor 1 (alpha) TIER2
230379 Acer2 alkaline ceramidase 2 TIER3
11847 Arg2 arginase type II TIER3
71952 Riox1 ribosomal oxygenase 1 TIER3
102871 Radx RPA1 related single stranded DNA binding protein, X-linked TIER3
192231 Hexim1 hexamethylene bis-acetamide inducible 1 TIER3
108937 Rnf169 ring finger protein 169 TIER3
381308 Ifi211 interferon activated gene 211 TIER3
16646 Kpna1 karyopherin subunit alpha 1 TIER3
22061 Trp63 transformation related protein 63 TIER3
277250 Kdm3b KDM3B lysine (K)-specific demethylase 3B TIER3
17184 Matr3 matrin 3 TIER3
67561 Wdr48 WD repeat domain 48 TIER3
76804 Kdm4c lysine (K)-specific demethylase 4C TIER3
12905 Cradd CASP2 and RIPK1 domain containing adaptor with death domain TIER3
20481 Ski ski sarcoma viral oncogene homolog (avian) TIER3
66911 Nudt16l1 nudix hydrolase 16 like 1 TIER3
93735 Wnt16 wingless-type MMTV integration site family, member 16 TIER3
15951 Ifi204 interferon activated gene 204 TIER3
330890 Piwil4 piwi-like RNA-mediated gene silencing 4 TIER3
216825 Usp22 ubiquitin specific peptidase 22 TIER3
18294 Ogg1 8-oxoguanine DNA-glycosylase 1 TIER3
22416 Wnt3a wingless-type MMTV integration site family, member 3A TIER3
233079 Ffar2 free fatty acid receptor 2 TIER3
70790 Ubr5 ubiquitin protein ligase E3 component n-recognin 5 TIER3
27007 Klrk1 killer cell lectin-like receptor subfamily K, member 1 TIER3
50518 a nonagouti TIER3
17765 Mtf2 metal response element binding transcription factor 2 TIER3
13018 Ctcf CCCTC-binding factor TIER3
218214 Kdm1b lysine (K)-specific demethylase 1B TIER3
20620 Plk2 polo like kinase 2 TIER3
27050 Rps3 ribosomal protein S3 TIER3
71458 Bcor BCL6 interacting corepressor TIER3
71701 Pnpt1 polyribonucleotide nucleotidyltransferase 1 TIER3
211323 Nrg1 neuregulin 1 TIER3
56480 Tbk1 TANK-binding kinase 1 TIER3
52679 E2f7 E2F transcription factor 7 TIER3
66824 Pycard PYD and CARD domain containing TIER3
18676 Phf2 PHD finger protein 2 TIER3
77976 Nuak1 NUAK family, SNF1-like kinase, 1 TIER3
12914 Crebbp CREB binding protein TIER2
382056 Crtc1 CREB regulated transcription coactivator 1 TIER3
102902673 Gm21992 predicted gene 21992 TIER3
214899 Kdm5a lysine demethylase 5A TIER3
320595 Phf8 PHD finger protein 8 TIER3
50883 Chek2 checkpoint kinase 2 TIER3
12028 Bax BCL2-associated X protein TIER2
98403 Zfp451 zinc finger protein 451 TIER3
22589 Atrx ATRX, chromatin remodeler TIER1
70556 Slc25a33 solute carrier family 25, member 33 TIER3
224826 Ubr2 ubiquitin protein ligase E3 component n-recognin 2 TIER3
27223 Trp53bp1 transformation related protein 53 binding protein 1 TIER3
225876 Kdm2a lysine (K)-specific demethylase 2A TIER3
26416 Mapk14 mitogen-activated protein kinase 14 TIER3
11308 Abi1 abl interactor 1 TIER3
12575 Cdkn1a cyclin dependent kinase inhibitor 1A TIER3
19821 Rnf2 ring finger protein 2 TIER3
74244 Atg7 autophagy related 7 TIER3
21652 Phf1 PHD finger protein 1 TIER3
67241 Smc6 structural maintenance of chromosomes 6 TIER3
83561 Tdrd1 tudor domain containing 1 TIER3
14991 H2-M3 histocompatibility 2, M region locus 3 TIER3
214162 Kmt2a lysine (K)-specific methyltransferase 2A TIER3
15364 Hmga2 high mobility group AT-hook 2 TIER3
102991 Ezhip EZH inhibitory protein TIER3
12544 Cdc45 cell division cycle 45 TIER3
56338 Txnip thioredoxin interacting protein TIER2
22194 Ube2e1 ubiquitin-conjugating enzyme E2E 1 TIER3
56876 Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor TIER3
72739 Zkscan3 zinc finger with KRAB and SCAN domains 3 TIER3
14375 Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 TIER3
170472 Recql5 RecQ protein-like 5 TIER3
52615 Suz12 SUZ12 polycomb repressive complex 2 subunit TIER3
237211 Fancb Fanconi anemia, complementation group B TIER3
268973 Nlrc4 NLR family, CARD domain containing 4 TIER3
69260 Ing2 inhibitor of growth family, member 2 TIER3
67941 Rps27l ribosomal protein S27-like TIER3
23955 Nek4 NIMA (never in mitosis gene a)-related expressed kinase 4 TIER3
13194 Ddb1 damage specific DNA binding protein 1 TIER3
51869 Rif1 replication timing regulatory factor 1 TIER3
20848 Stat3 signal transducer and activator of transcription 3 TIER3
12578 Cdkn2a cyclin dependent kinase inhibitor 2A TIER3
21898 Tlr4 toll-like receptor 4 TIER3
21386 Tbx3 T-box 3 TIER3
22289 Kdm6a lysine (K)-specific demethylase 6A TIER3
68149 Otub2 OTU domain, ubiquitin aldehyde binding 2 TIER3
11450 Adipoq adiponectin, C1Q and collagen domain containing TIER3
15902 Id2 inhibitor of DNA binding 2 TIER3
75317 Parpbp PARP1 binding protein TIER3
107260 Otub1 OTU domain, ubiquitin aldehyde binding 1 TIER3
58230 Rnf8 ring finger protein 8 TIER3
225131 Wac WW domain containing adaptor with coiled-coil TIER3
20371 Foxp3 forkhead box P3 TIER3
77035 Kdm8 lysine (K)-specific demethylase 8 TIER3
26914 Macroh2a1 macroH2A.1 histone TIER3
19373 Rag1 recombination activating 1 TIER3
67768 N6amt1 N-6 adenine-specific DNA methyltransferase 1 (putative) TIER3
226781 Slc30a10 solute carrier family 30, member 10 TIER3
18140 Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 TIER3
545725 Mterf1a mitochondrial transcription termination factor 1a TIER3
12317 Calr calreticulin TIER3
22210 Ube2b ubiquitin-conjugating enzyme E2B TIER3
226026 Smc5 structural maintenance of chromosomes 5 TIER3
14235 Foxm1 forkhead box M1 TIER3
71890 Mad2l2 MAD2 mitotic arrest deficient-like 2 TIER3
69009 Thap7 THAP domain containing 7 TIER3
19650 Rbl1 RB transcriptional corepressor like 1 TIER3
76073 Pcgf5 polycomb group ring finger 5 TIER3
21750 Terf2 telomeric repeat binding factor 2 TIER3
93759 Sirt1 sirtuin 1 TIER3
98558 Mael maelstrom spermatogenic transposon silencer TIER3
81601 Kat5 K(lysine) acetyltransferase 5 TIER3
73747 Shld1 shieldin complex subunit 1 TIER3
225896 Ubxn1 UBX domain protein 1 TIER3
77531 Anks1b ankyrin repeat and sterile alpha motif domain containing 1B TIER3
14582 Gfi1b growth factor independent 1B TIER3
74068 Asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 TIER3
12326 Camk4 calcium/calmodulin-dependent protein kinase IV TIER3
20926 Supt6 SPT6, histone chaperone and transcription elongation factor TIER3
72584 Cul4b cullin 4B TIER3
16396 Itch itchy, E3 ubiquitin protein ligase TIER3
20466 Sin3a transcriptional regulator, SIN3A (yeast) TIER3
19763 Ring1 ring finger protein 1 TIER3
69885 Aunip aurora kinase A and ninein interacting protein TIER3
338438 Hymai hydatidiform mole associated and imprinted transcript TIER3
107817 Jmjd6 jumonji domain containing 6 TIER3
114142 Foxp2 forkhead box P2 TIER2
54343 Atf7ip activating transcription factor 7 interacting protein TIER3
13619 Phc1 polyhomeotic 1 TIER3
17263 Meg3 maternally expressed 3 TIER3
13653 Egr1 early growth response 1 TIER2
57320 Park7 Parkinson disease (autosomal recessive, early onset) 7 TIER3
20821 Trim21 tripartite motif-containing 21 TIER3
77782 Polq polymerase (DNA directed), theta TIER3
21385 Tbx2 T-box 2 TIER3
193796 Kdm4b lysine (K)-specific demethylase 4B TIER3
74355 Smchd1 SMC hinge domain containing 1 TIER3
53892 Ppm1d protein phosphatase 1D magnesium-dependent, delta isoform TIER3
319955 Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 TIER3
13436 Dnmt3b DNA methyltransferase 3B TIER3
94244 Fkbp6 FK506 binding protein 6 TIER3
106014251 Gm28043 predicted gene, 28043 TIER3
230738 Zc3h12a zinc finger CCCH type containing 12A TIER3
20587 Smarcb1 SWI/SNF related BAF chromatin remodeling complex subunit B1 TIER3
217218 Atxn7l3 ataxin 7-like 3 TIER3
17246 Mdm2 transformed mouse 3T3 cell double minute 2 TIER3
170826 Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta TIER3
16647 Kpna2 karyopherin subunit alpha 2 TIER3
116848 Baz2a bromodomain adjacent to zinc finger domain, 2A TIER3
28019 Ing4 inhibitor of growth family, member 4 TIER3
214763 Cgas cyclic GMP-AMP synthase TIER3
56353 Rybp RING1 and YY1 binding protein TIER3
214572 Prmt7 protein arginine N-methyltransferase 7 TIER3
14056 Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit TIER3
114774 Pawr PRKC, apoptosis, WT1, regulator TIER3
70238 Rnf168 ring finger protein 168 TIER3
50721 Sirt6 sirtuin 6 TIER3
74143 Opa1 OPA1, mitochondrial dynamin like GTPase TIER3
68077 Nop53 NOP53 ribosome biogenesis factor TIER3
22083 Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component TIER3
59026 Huwe1 HECT, UBA and WWE domain containing 1 TIER3
24088 Tlr2 toll-like receptor 2 TIER3
14134 Fcnb ficolin B TIER3
69587 Pcgf3 polycomb group ring finger 3 TIER3
19697 Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) TIER3
21849 Trim28 tripartite motif-containing 28 TIER3
69821 Mterf4 mitochondrial transcription termination factor 4 TIER3
17319 Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) TIER3
20851 Stat5b signal transducer and activator of transcription 5B TIER2
12043 Bcl2 B cell leukemia/lymphoma 2 TIER2
56275 Rbm14 RNA binding motif protein 14 TIER3
66645 Pspc1 paraspeckle protein 1 TIER3
209200 Dtx3l deltex 3-like, E3 ubiquitin ligase TIER3
108829 Jmjd1c jumonji domain containing 1C TIER3
216151 Polrmt polymerase (RNA) mitochondrial (DNA directed) TIER3
54427 Dnmt3l DNA methyltransferase 3-like TIER3
67071 Rps6ka6 ribosomal protein S6 kinase polypeptide 6 TIER3
194908 Pld6 phospholipase D family member 6 TIER3
15201 Hells helicase, lymphoid specific TIER3
20937 Suv39h1 suppressor of variegation 3-9 1 TIER3
72512 Sting1 stimulator of interferon response cGAMP interactor 1 TIER3
71514 Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) TIER3
223970 Rmi2 RecQ mediated genome instability 2 TIER3
12051 Bcl3 B cell leukemia/lymphoma 3 TIER3
76781 Mettl4 methyltransferase 4, N6-adenosine TIER3
20677 Sox4 SRY (sex determining region Y)-box 4 TIER3
66090 Ypel3 yippee like 3 TIER3
226695 Ifi205 interferon activated gene 205 TIER3
331623 Bend3 BEN domain containing 3 TIER3
12190 Brca2 breast cancer 2, early onset TIER3
16468 Jarid2 jumonji and AT-rich interaction domain containing 2 TIER3
69188 Kmt2e lysine (K)-specific methyltransferase 2E TIER3
20807 Srf serum response factor TIER3
11920 Atm ataxia telangiectasia mutated TIER1
67141 Fbxo5 F-box protein 5 TIER3
59027 Nampt nicotinamide phosphoribosyltransferase TIER3
12189 Brca1 breast cancer 1, early onset TIER3
30951 Cbx8 chromobox 8 TIER3
21353 Tank TRAF family member-associated Nf-kappa B activator TIER3
246196 Zfp277 zinc finger protein 277 TIER3
69076 Triap1 TP53 regulated inhibitor of apoptosis 1 TIER3
12571 Cdk6 cyclin dependent kinase 6 TIER3
22160 Twist1 twist basic helix-loop-helix transcription factor 1 TIER3
236312 Ifi209 interferon activated gene 209 TIER3
17257 Mecp2 methyl CpG binding protein 2 TIER2
107815 Scml2 Scm polycomb group protein like 2 TIER3
68729 Trim37 tripartite motif-containing 37 TIER3
56484 Foxo3 forkhead box O3 TIER3
66143 Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 TIER3
72634 Tdrkh tudor and KH domain containing protein TIER3
18507 Pax5 paired box 5 TIER3
15461 Hras Harvey rat sarcoma virus oncogene TIER3
56632 Sphk2 sphingosine kinase 2 TIER3
83456 Mov10l1 Mov10 like RISC complex RNA helicase 1 TIER3
14194 Fh1 fumarate hydratase 1 TIER3
14897 Trip12 thyroid hormone receptor interactor 12 TIER3
18854 Pml promyelocytic leukemia TIER3
194388 Tet3 tet methylcytosine dioxygenase 3 TIER3
12389 Cav1 caveolin 1, caveolae protein TIER3
26395 Map2k1 mitogen-activated protein kinase kinase 1 TIER3
216343 Tph2 tryptophan hydroxylase 2 TIER3
230784 Sesn2 sestrin 2 TIER3
338523 Kdm7a lysine (K)-specific demethylase 7A TIER3
12579 Cdkn2b cyclin dependent kinase inhibitor 2B TIER3
75698 Shld2 shieldin complex subunit 2 TIER3
53890 Sart3 squamous cell carcinoma antigen recognized by T cells 3 TIER3
20181 Rxra retinoid X receptor alpha TIER1
15278 Tfb2m transcription factor B2, mitochondrial TIER3
15460 Hr lysine demethylase and nuclear receptor corepressor TIER3
73945 Otud4 OTU domain containing 4 TIER3
26386 Hsf4 heat shock transcription factor 4 TIER3
93765 Ube2n ubiquitin-conjugating enzyme E2N TIER3
214669 L3mbtl2 L3MBTL2 polycomb repressive complex 1 subunit TIER3
210009 Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase TIER3
12015 Bad BCL2-associated agonist of cell death TIER2
56190 Rbm38 RNA binding motif protein 38 TIER3
21752 Tert telomerase reverse transcriptase TIER3
22290 Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked TIER3
74691 Tdrd9 tudor domain containing 9 TIER3
22715 Zfp57 zinc finger protein 57 TIER3
58203 Zbp1 Z-DNA binding protein 1 TIER3
244694 Kdm4d lysine (K)-specific demethylase 4D TIER3
68790 Fendrr Foxf1 adjacent non-coding developmental regulatory RNA TIER3
18779 Pla2r1 phospholipase A2 receptor 1 TIER3
208595 Mterf1b mitochondrial transcription termination factor 1b TIER3
18753 Prkcd protein kinase C, delta TIER3
14683 Gnas GNAS complex locus TIER3
56802 Gnasas1 GNAS antisense RNA 1 TIER3
15950 Ifi203 interferon activated gene 203 TIER3
12010 B2m beta-2 microglobulin TIER3
50849 Rnf10 ring finger protein 10 TIER3
83383 Tfap4 transcription factor AP4 TIER3
12366 Casp2 caspase 2 TIER3
140858 Wdr5 WD repeat domain 5 TIER3
235497 Leo1 Leo1, Paf1/RNA polymerase II complex component TIER3
22224 Usp10 ubiquitin specific peptidase 10 TIER3
228607 Mavs mitochondrial antiviral signaling protein TIER3
383619 Aim2 absent in melanoma 2 TIER3
15499 Hsf1 heat shock factor 1 TIER3
54624 Paf1 Paf1, RNA polymerase II complex component TIER3
57913 Pidd1 p53 induced death domain protein 1 TIER3
17165 Mapkapk5 MAP kinase-activated protein kinase 5 TIER3
16653 Kras Kirsten rat sarcoma viral oncogene homolog TIER3
22658 Pcgf2 polycomb group ring finger 2 TIER3
17703 Msx3 msh homeobox 3 TIER3
17191 Mbd2 methyl-CpG binding domain protein 2 TIER2
17920 Myo6 myosin VI TIER3
11350 Abl1 c-abl oncogene 1, non-receptor tyrosine kinase TIER3
30841 Kdm2b lysine (K)-specific demethylase 2B TIER3
53314 Batf basic leucine zipper transcription factor, ATF-like TIER3
18145 Npc1 NPC intracellular cholesterol transporter 1 TIER2
78896 Ecrg4 ECRG4 augurin precursor TIER3
23942 Mta2 metastasis-associated gene family, member 2 TIER3
69837 Pcgf1 polycomb group ring finger 1 TIER3
20592 Kdm5d lysine demethylase 5D TIER3
545384 Ifi214 interferon activated gene 214 TIER3
54633 Pqbp1 polyglutamine binding protein 1 TIER3
432763 Prr7 proline rich 7 (synaptic) TIER3
12053 Bcl6 B cell leukemia/lymphoma 6 TIER3
57783 Tnip1 TNFAIP3 interacting protein 1 TIER3
20375 Spi1 Spi-1 proto-oncogene TIER3
13433 Dnmt1 DNA methyltransferase 1 TIER3
66409 Rsl1d1 ribosomal L1 domain containing 1 TIER3
12166 Bmpr1a bone morphogenetic protein receptor, type 1A TIER3
22059 Trp53 transformation related protein 53 TIER3
233900 Rnf40 ring finger protein 40 TIER3
11793 Atg5 autophagy related 5 TIER3
56282 Mrpl12 mitochondrial ribosomal protein L12 TIER3
26875 Pclo piccolo (presynaptic cytomatrix protein) TIER3
113002583 Shld3 shieldin complex subunit 3 TIER3
26406 Map3k3 mitogen-activated protein kinase kinase kinase 3 TIER3
73708 Dppa3 developmental pluripotency-associated 3 TIER3
17450 Morc1 microrchidia 1 TIER3
16452 Jak2 Janus kinase 2 TIER3
94232 Ubqln4 ubiquilin 4 TIER3
71981 Tdrd12 tudor domain containing 12 TIER3
99890 Prmt6 protein arginine N-methyltransferase 6 TIER3
22596 Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 TIER3
68501 Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase TIER3
77683 Ehmt1 euchromatic histone methyltransferase 1 TIER3
214575 Tdrd5 tudor domain containing 5 TIER3
19941 Rpl26 ribosomal protein L26 TIER3
56812 Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 TIER3
78412 Cyren cell cycle regulator of NHEJ TIER3
269523 Vcp valosin containing protein TIER3
110147 Ehmt2 euchromatic histone lysine N-methyltransferase 2 TIER3
13016 Ctbp1 C-terminal binding protein 1 TIER3
15194 Htt huntingtin TIER3
236904 Klhl15 kelch-like 15 TIER3
246198 Mllt6 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 TIER3
74238 Mterf2 mitochondrial transcription termination factor 2 TIER3
13206 Ddx4 DEAD box helicase 4 TIER3
243655 Klre1 killer cell lectin-like receptor family E member 1 TIER3
20591 Kdm5c lysine demethylase 5C TIER3
107986 Ddb2 damage specific DNA binding protein 2 TIER3
104263 Kdm3a lysine (K)-specific demethylase 3A TIER3
20617 Snca synuclein, alpha TIER3
664799 Ctcfl CCCTC-binding factor like TIER3
109331 Rnf20 ring finger protein 20 TIER3
50755 Fbh1 F-box DNA helicase 1 TIER3
53610 Nono non-POU-domain-containing, octamer binding protein TIER3
12217 Bsn bassoon TIER3
51788 H2az1 H2A.Z variant histone 1 TIER2
244349 Kat6a K(lysine) acetyltransferase 6A TIER3
19090 Prkdc protein kinase, DNA activated, catalytic polypeptide TIER3
67278 Pagr1a PAXIP1 associated glutamate rich protein 1A TIER3
56448 Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 TIER3
57741 Noc2l NOC2 like nucleolar associated transcriptional repressor TIER3
56717 Mtor mechanistic target of rapamycin kinase TIER1
15289 Hmgb1 high mobility group box 1 TIER3
21780 Tfam transcription factor A, mitochondrial TIER3
Term Name Aspect Overlap Size
GO:0090398 cellular senescence BP 0 58
GO:0032776 obsolete DNA methylation on cytosine BP 0 0
GO:0002218 activation of innate immune response BP 0 189
GO:0040030 obsolete regulation of molecular function, epigenetic BP 0 0
GO:0045304 regulation of establishment of competence for transformation BP 0 0
GO:0090085 regulation of protein deubiquitination BP 0 11
GO:0006587 serotonin biosynthetic process from tryptophan BP 0 2
GO:0099527 postsynapse to nucleus signaling pathway BP 0 14
GO:0042772 DNA damage response, signal transduction resulting in transcription BP 0 1
GO:0090402 oncogene-induced cell senescence BP 0 8
GO:2000772 regulation of cellular senescence BP 1 51
GO:0006390 mitochondrial transcription BP 0 20
GO:0030330 DNA damage response, signal transduction by p53 class mediator BP 1 38
GO:0060785 regulation of apoptosis involved in tissue homeostasis BP 0 2
GO:0099526 presynapse to nucleus signaling pathway BP 0 1
GO:0031938 obsolete regulation of chromatin silencing at telomere BP 0 0
GO:0090403 oxidative stress-induced premature senescence BP 0 4
GO:0031057 obsolete negative regulation of histone modification BP 0 0
GO:0016574 obsolete histone ubiquitination BP 0 0
GO:0016577 obsolete histone demethylation BP 0 0
GO:0070994 detection of oxidative stress BP 0 2
GO:0006306 obsolete DNA methylation BP 0 0
GO:0045738 negative regulation of DNA repair BP 0 40
GO:0090400 stress-induced premature senescence BP 0 7

Rat Research Focus

Epigenetics, DNA methylation, gene expression, histone modifications, chromatin, immunometabolism, cell growth, apoptosis, anxiety (stress), learning and memory, social interaction, developmental disorders (autism), metabolic disease (triple-negative breast cancer, lung cancer), neurodegeneration (Niemann Pick disease, Alzhiemer's disease)

Gene ID Symbol Name Tier
361783 Zfp57 zinc finger protein 57 TIER3
294007 Pprc1 PPARG related coactivator 1 TIER3
25125 Stat3 signal transducer and activator of transcription 3 TIER3
310769 Wdr77 WD repeat domain 77 TIER3
54244 Crebbp CREB binding protein TIER2
296732 Smarcd3 SWI/SNF related BAF chromatin remodeling complex subunit D3 TIER3
287585 Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D TIER3
24413 Nr3c1 nuclear receptor subfamily 3, group C, member 1 TIER1
683923 Bend3 BEN domain containing 3 TIER3
140938 Psmc3ip PSMC3 interacting protein TIER3
114206 Tmf1 TATA element modulatory factor 1 TIER3
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 TIER3
83724 Ncoa2 nuclear receptor coactivator 2 TIER3
113898 Prdx5 peroxiredoxin 5 TIER3
246047 Calcoco1 calcium binding and coiled coil domain 1 TIER3
24890 Esr1 estrogen receptor 1 TIER1
303201 Usp22 ubiquitin specific peptidase 22 TIER3
171051 Cabp1 calcium binding protein 1 TIER3
29355 Pkn1 protein kinase N1 TIER3
29138 Bsn bassoon (presynaptic cytomatrix protein) TIER3
170578 Asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 TIER3
444984 Dnmt3a DNA methyltransferase 3 alpha TIER3
315606 Kmt2a lysine methyltransferase 2A TIER3
364039 Mael maelstrom spermatogenic transposon silencer TIER3
29424 Htt huntingtin TIER3
314721 Anks1b ankyrin repeat and sterile alpha motif domain containing 1B TIER3
689972 Piwil4 piwi-like RNA-mediated gene silencing 4 TIER3
362078 Ehmt1 euchromatic histone lysine methyltransferase 1 TIER3
299343 Tdrd9 tudor domain containing 9 TIER3
25050 Camk4 calcium/calmodulin-dependent protein kinase IV TIER3
300367 Med17 mediator complex subunit 17 TIER3
289181 Dcaf6 DDB1 and CUL4 associated factor 6 TIER3
290947 Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase TIER3
294071 Hells helicase, lymphoid specific TIER3
685258 Eny2 ENY2, transcription and export complex 2 subunit TIER3
289129 Tdrd5 tudor domain containing 5 TIER3
361103 Zmiz1 zinc finger, MIZ-type containing 1 TIER3
84584 Ncoa3 nuclear receptor coactivator 3 TIER3
304567 Pus1 pseudouridine synthase 1 TIER3
497991 Med1 mediator complex subunit 1 TIER3
252891 Sra1 steroid receptor RNA activator 1 TIER3
306819 Kdm1b lysine demethylase 1B TIER3
84350 Dnmt1 DNA methyltransferase 1 TIER3
313436 Zcchc12 zinc finger CCHC-type containing 12 TIER3
292925 Tsg101 tumor susceptibility 101 TIER3
100360757 Ctcfl1 CCCTC-binding factor like 1 TIER3
112400 Nrg1 neuregulin 1 TIER3
361801 Rxrb retinoid X receptor beta TIER3
299607 Med16 mediator complex subunit 16 TIER3
500569 Kdm1a lysine demethylase 1A TIER3
312299 Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit TIER3
291567 Ppargc1b PPARG coactivator 1 beta TIER3
360712 Morc1 MORC family CW-type zinc finger 1 TIER3
83516 Ppargc1a PPARG coactivator 1 alpha TIER3
306007 Ccar2 cell cycle and apoptosis regulator 2 TIER3
54250 Fgf2 fibroblast growth factor 2 TIER1
310090 Ddx4 DEAD-box helicase 4 TIER3
361402 Prmt7 protein arginine methyltransferase 7 TIER3
288309 N6amt1 N-6 adenine-specific DNA methyltransferase 1 TIER3
361849 Ccar1 cell division cycle and apoptosis regulator 1 TIER3
681766 Stpg4 sperm-tail PG-rich repeat containing 4 TIER3
300141 Mov10l1 Mov10 like RNA helicase 1 TIER3
116464 Ncoa6 nuclear receptor coactivator 6 TIER3
289783 Zmiz2 zinc finger, MIZ-type containing 2 TIER3
306011 Piwil2 piwi-like RNA-mediated gene silencing 2 TIER3
171379 Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 TIER3
287366 Pld6 phospholipase D family, member 6 TIER3
361295 Ss18 SS18 subunit of BAF chromatin remodeling complex TIER3
83726 Ctcf CCCTC-binding factor TIER3
25023 Prkcb protein kinase C, beta TIER3
297576 Dppa3 developmental pluripotency-associated 3 TIER3
117536 Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor TIER3
296474 Helz2 helicase with zinc finger 2 TIER3
680172 Mbd2 methyl-CpG binding domain protein 2 TIER1
304601 Baz2a bromodomain adjacent to zinc finger domain, 2A TIER3
81522 Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase TIER3
311968 Kmt2e lysine methyltransferase 2E TIER3
309165 Rela RELA proto-oncogene, NF-kB subunit TIER3
689909 Ccdc62 coiled-coil domain containing 62 TIER3
24224 Bcl2 BCL2, apoptosis regulator TIER1
498995 Ncoa7 nuclear receptor coactivator 7 TIER3
361724 Mta2 metastasis associated 1 family, member 2 TIER3
362414 Tada3 transcriptional adaptor 3 TIER3
81634 Actn1 actinin, alpha 1 TIER3
313929 Ncoa1 nuclear receptor coactivator 1 TIER3
291245 Actn2 actinin alpha 2 TIER3
680576 Tet3 tet methylcytosine dioxygenase 3 TIER3
361798 Ehmt2 euchromatic histone lysine methyltransferase 2 TIER3
498704 Prr7 proline rich 7 (synaptic) TIER3
363026 Carm1 coactivator-associated arginine methyltransferase 1 TIER3
56768 Pclo piccolo (presynaptic cytomatrix protein) TIER3
63836 Actn4 actinin alpha 4 TIER3
89819 Bud31 BUD31 homolog TIER3
25126 Stat5b signal transducer and activator of transcription 5B TIER1
25664 Pparg peroxisome proliferator-activated receptor gamma TIER3
24896 Gnas GNAS complex locus TIER3
288710 Rnf10 ring finger protein 10 TIER3
294030 Sfr1 SWI5-dependent homologous recombination repair protein 1 TIER3
684527 Crtc1 CREB regulated transcription coactivator 1 TIER3
24887 Bax BCL2 associated X, apoptosis regulator TIER1
117062 Hmga1 high mobility group AT-hook 1 TIER3
288597 Fkbp6 FKBP prolyl isomerase family member 6 TIER3
307151 Bmi1 BMI1 proto-oncogene, polycomb ring finger TIER3
24514 Jak2 Janus kinase 2 TIER3
303181 Wnt3a Wnt family member 3A TIER3
691014 Dppa3l1 developmental pluripotency associated 3-like 1 TIER3
29382 Ctbp1 C-terminal binding protein 1 TIER3
312800 Atf7ip activating transcription factor 7 interacting protein TIER3
170900 Rbm14 RNA binding motif protein 14 TIER3
85245 Kpna2 karyopherin subunit alpha 2 TIER3
288064 Kpna1 karyopherin subunit alpha 1 TIER3
292129 Tdrd1 tudor domain containing 1 TIER3
103691034 Peg3 paternally expressed 3 TIER1
29386 Mecp2 methyl CpG binding protein 2 TIER1
316731 Mettl4 methyltransferase 4, N6-adenosine TIER3
316219 Trerf1 transcriptional regulating factor 1 TIER3
309680 Dnmt3l DNA methyltransferase 3 like TIER3
116698 Trim28 tripartite motif-containing 28 TIER3
287734 Atxn7l3 ataxin 7-like 3 TIER3
689639 Tdrd12 tudor domain containing 12 TIER3
498358 Slc30a9 solute carrier family 30 member 9 TIER3
310652 Tdrkh tudor and KH domain containing TIER3
444985 Dnmt3b DNA methyltransferase 3 beta TIER3
79249 Abi1 abl-interactor 1 TIER3
291691 Brd8 bromodomain containing 8 TIER3
Term Name Aspect Overlap Size
GO:0099527 postsynapse to nucleus signaling pathway BP 0 14
GO:0006306 obsolete DNA methylation BP 0 0
GO:0032776 obsolete DNA methylation on cytosine BP 0 0
GO:0030374 obsolete nuclear receptor coactivator activity MF 0 0
GO:0099526 presynapse to nucleus signaling pathway BP 0 1
GO:0060785 regulation of apoptosis involved in tissue homeostasis BP 0 2